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Systematic Reviews

Introduction

 

What is a Systematic Review?

The Cochrane Collaboration definition:

"A systematic review summarises the results of available carefully designed healthcare studies (controlled trials) and provides a high level of evidence on the effectiveness of healthcare interventions.  Judgments may be made about the evidence and inform recommendations for healthcare".
 

Characteristics of a systematic review 

  • Clearly stated set of objectives with pre-defined eligibility criteria for studies. 
  • An explicit, reproducible methodology 
  • A systematic search that attempts to identify all studies that would meet the eligibility criteria
  • An assessment of the validity of the findings of the included studies, for example through the assessment of risk of bias
  • A systematic presentation, and synthesis, of the characteristics and findings of the included studies 


Key organisations that produce systematic reviews:

Cochrane Collaboration 
Cochrane Handbook 

JBI (Joanna Briggs Institution)
JBI Manual for evidence synthesis

Campbell Collaboration 
The Campbell Collaboration has a social science focus

Other types of review

High quality systematic reviews of complex questions can involve large teams of researchers and can take months or even years to complete. It is accepted good practice to have at least two researchers working on any systematic review to minimize bias in the selection of studies and the extraction of data. 

The time you have available and whether you are working on your own will impact on the level of review that you can complete. 

There are a range of other types of reviews including:

  • ​Literature reviews
  • Systematic literature reviews 
  • Scoping reviews
  • Rapid reviews

There is a useful summary of types of reviews from the PhD on Track web resource.  This also has links to further reading about review types. 

Useful books

Cochrane Handbook for Systematic Reviews of Interventions

The revised edition of the Handbook offers the only guide on how to conduct, report and maintain a Cochrane Review.

Systematic Approaches to a Successful Literature Review

Doing a Systematic Review

An Introduction to Systematic Reviews

How to read a paper : the basics of evidence-based medicine and healthcare

A recommended book. See Chapter 2: Searching the literature.

Help and support

Your Subject Librarian will be able to give advice on the following aspects of your Systematic Review:

  • Constructing an effective search strategy
  • Database selection
  • Reference management

 

For subject-specific support please contact your Subject Librarian.

Additional support

Cochrane Handbook for Systematic Reviews of Interventions - key resource for those carrying out a Cochrane review and any other systematic review of interventions

Epistemonikos - database of evidence-based healthcare systematic reviews maintained by the Epistemonikos Foundation

JBI Manual for Evidence Synthesis - guidance for conducting a JBI systematic review

Campbell Collaboration - social science systematic reviews 

PROSPERO - protocol register useful for searching for other reviews currently ongoing and to register your protocol

PRISMA Statement - reporting guidelines for a systematic review including a reporting checklist and a flow diagram for recording your search strategy

University of Bristol library subject guides - guides related to your subject area

CASP-UK - Critical Appraisal Skills Programme

CEBM has tools for evaluating RCTs, systematic reviews and diagnostics

Bristol Medical School short courses. - such as Introduction to Systematic Reviews and Meta-Analysis and Introduction to Network Meta-Analysis.  There are also Materials and Recordings courses that are free of charge for University of Bristol staff members or Postgraduate Research students.  They are ideal for self-paced learning, to dip into a new subject area or simply refresh your knowledge.